| | Sin comenzar | Mar, 20 AGO 2019 |  APOEL | 21:00 | Ajax |
|
| | Sin comenzar | Mar, 20 AGO 2019 |  LASK Linz | 21:00 | Club Brugge |
|
| | Sin comenzar | Mar, 20 AGO 2019 |  CFR Cluj | 21:00 | Slavia Praha |
|
| | Sin comenzar | Mie, 21 AGO 2019 |  Young Boys | 21:00 | Crvena Zvezda |
|
| | Sin comenzar | Mie, 21 AGO 2019 |  Olympiacos Piraeus | 21:00 | FK Krasnodar |
|
| | Sin comenzar | Mie, 21 AGO 2019 |  Dinamo Zagreb | 21:00 | Rosenborg BK |
|
| | Sin comenzar | Jue, 22 AGO 2019 |  Astana | 16:00 | BATE Borisov |
|
| | Sin comenzar | Jue, 22 AGO 2019 |  Ararat-Armenia | 17:00 | F91 Dudelange |
|
| | Sin comenzar | Jue, 22 AGO 2019 |  Malmö | 19:00 | Bnei Yehuda Tel Aviv |
|
| | Sin comenzar | Jue, 22 AGO 2019 |  Sūduva | 19:00 | Ferencvárosi |
|
| | Sin comenzar | Jue, 22 AGO 2019 |  Ludogorets | 19:30 | Maribor |
|
| | Sin comenzar | Jue, 22 AGO 2019 |  Feyenoord | 19:30 | Hapoel Be'er Sheva |
|
